Identification of the Possible Negative Effect of the Brucite Drilling Reagent on the Employees Involved in the Wells Construction


In the technological processes of oil and gas wells construction, a variety of general-purpose inorganic chemical reagents are used. The ingress of these reagents into the body of drilling enterprises employees together with the inhaled air, ingested food (through the pores and mucous membrane) is currently not sufficiently studied. The work investigated the effect of the Brucite drilling reagent on the lung tissue of rats of the non-linear albino line. With the inhalation of the Brucite drilling reagent to rats, the dystrophic processes were observed in their lungs, which were accompanied by the development of chronic inflammation and an acute macrophage reaction. There was a significant increase in the size of perivascular infiltrates compared to the control (13370 ± 248.6) μm2) with 14-day administration of particles of the Brucite drilling reagent — (14867.21 ± 369.29) μm2, with 30-day administration — 15853, 87 ± 126.57. Also, morphometric analysis showed a significant decrease in the area of alveolar space, and the area of medium-caliber bronchus. In the lungs, the formation of many airless areas was noted, alternating with emphysematous — altered, the severity of which increased with the duration of exposure to the drilling reagent. The consequence of work with Brucite drilling reagent of the drilling enterprises employees can be professional, acute, and chronic diseases of the lungs, as well as specific sensitization of the body caused by the exposure to dust particles.  In the future, it is planned to conduct a statistical analysis of the incidence rates with temporary disability, occupational diseases, and occupational poisoning among the employees in contact with the Brucite drilling reagent, and the development of efficient measures to reduce the harmful effects of the Brucite drilling reagent on the certain categories of specialists at the drilling enterprises.

1. Shah S.N., Shanker N.H., Ogugbue C.C. Future challenges of drilling fluids and their rheological measurements. Available at: (accessed: March 15, 2021).
2. Bloys B., Davis N., Smolen B., Bailey L., Houwen O., Reid P., Sherwood J., Fraser L., Hodder M. Designing and managing drilling fluid. Available at: (accessed: March 15, 2021).
3. Okpokwasili G.C., Nnubia C. Effects of drilling fluids on marine bacteria from a Nigerian offshore oilfield. Environmental Management. 1995. Vol. 19. № 6. pp. 923–929.
4. Wieczorek D., Marchut-Mikolajczyk O., Bielecki S., Kwapisz E. Phytotests as tools for monitoring the bioremediation process of soil contaminated with diesel oil. Biotechnology Letters. 2012. Vol. 93. № 4. pp. 431–439.
5. Candler J.E., Rushing J.H., Leuterman A.J.J. Synthetic-based mud systems offer environmental benefits over traditional mud systems. SPE/EPA Exploration and Production Environmental Conference. San Antonio, 1993. pp. 485–499.
6. Mcguire T.C., Hughes J.B. Effects of surfactants on the dechlorination of chlorinated ethenes. Environmental Toxicology and Chemistry. 2003. Vol. 22. № 11. pp. 131–140. 
7. Lambert R.J., Pearson J. Susceptibility testing: accurate and reproducible minimum inhibitory concentration (MICPearson) and non-inhibitory concentration (NIC) values. Applied Microbiology. 2000. Vol. 88. № 5. pp. 784–790. 
8. Bulatov A.I., Dolgov S.V. Satellite of the driller: reference book. In 2 books. Bk. 1. 2-e izd. Мoscow: Nedra, 2014. 379 p. (In Russ.).
9. Ryazanov Ya.A. Encyclopedia of drilling fluids. Orenburg: Letopis, 2005. 664 p. (In Russ.).
10. Khodja M., Khodja-Saber M., Canselier J.P., Cohaut N., Bergaya F. Drilling fluid technology: performances and environmental considerations. Available at: (accessed: March 15, 2021).
11. Saksonov M.N., Balayan A.E., Barkhatova O.A. Determination of wastes hazard class by biotesting methods. Izvestiya Irkutskoy gosudarstvennoy ekonomicheskoy akademii = The Bulletin of Irkutsk State University. 2011. № 1. pp. 21–23. (In Russ.).
12. Gimranova G.G., Bakirov A.B. Features of the employee occupational morbidity in the oil industry. Vseros. nauch.-prakt. konf. «Neft i zdorove»: sb. nauch. tr. (All-Russian scientific and practical conference «Oil and Health»: research papers collection). Ufa: Ufimskiy nauchno-issledovatelskiy institut meditsiny truda i ekologii cheloveka, 2009. pp. 156–160. (In Russ.).
DOI: 10.24000/0409-2961-2021-9-75-80
Year: 2021
Issue num: September
Keywords : occupational safety personal protective equipment drilling reagent lungs area of perivascular infiltrates air pollution of the working area harmful effects alveoli